This web tool offers the possibility to identify ring analogs that based on the structure-activity data from a large corpus of medicinal chemistry literature lead to improved biological activity. See the theoretical background in our article in Eur. J. Med. Chem.. Click simply the ring image to see its recommended analogs. The 2 numbers shown for each analog provide information how the average bioactivity is improved by the replacement (in log10 scale) and on how many literature sources this data are based on.
You may wish to check also other web tools for medicinal chemists available on this site.
