Ring Replacement Recommender v2022.02

This web tool offers the possibility to identify ring analogs that based on the structure-activity data from a large corpus of medicinal chemistry literature lead to improved biological activity. See the theoretical background link to publication will appear here soon. Click simply the ring image to see its recommended analogs. The 2 numbers shown for each analog provide information how the average bioactivity is improved by the replacement (in log10 scale) and on how many literature sources this data are based on.